RNA Interference in Infectious Tropical Diseases

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RNA interference in infectious tropical diseases.

Introduction of double-stranded RNA (dsRNA) into some cells or organisms results in degradation of its homologous mRNA, a process called RNA interference (RNAi). The dsRNAs are processed into short interfering RNAs (siRNAs) that subsequently bind to the RNA-induced silencing complex (RISC), causing degradation of target mRNAs. Because of this sequence-specific ability to silence target genes, R...

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ژورنال

عنوان ژورنال: The Korean Journal of Parasitology

سال: 2008

ISSN: 0023-4001

DOI: 10.3347/kjp.2008.46.1.1